Conjugation of some NSAIDs with 5-phenyl-2-aminothiazole for reduced ulcerogenicity
| dc.contributor.author | Verma A.; Das N.; Dhanawat M.; Shrivastava S.K. | |
| dc.date.accessioned | 2025-05-24T09:57:43Z | |
| dc.description.abstract | Analgesic drugs containing free acidic group were reacted with N, N' carbonyldiimidazole to prepare the acylimidazole derivatives. They were further reacted with 5-phenyl-2-amino thiazole nucleus to obtain the corresponding amides. All the compounds were found to retain analgesic-antiinflammatory activities with much lesser NSAID-induced GI complications when compared with the standard. | |
| dc.identifier.doi | DOI not available | |
| dc.identifier.uri | http://172.23.0.11:4000/handle/123456789/22450 | |
| dc.relation.ispartofseries | Thai Journal of Pharmaceutical Sciences | |
| dc.title | Conjugation of some NSAIDs with 5-phenyl-2-aminothiazole for reduced ulcerogenicity |