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Transition-Metal-Free Synthesis of 7-Aminocoumarins from 7-Hydroxycoumarins Using Multifunctional Reagent
| dc.contributor.author | Indurthi H.K.; Das S.; Saha P.; Sharma D.K. | |
| dc.date.accessioned | 2025-05-23T10:56:28Z | |
| dc.description.abstract | We have successfully synthesized N-substituted 7-aminocoumarins by reacting 7-hydroxycoumarins with amines using 5,6-dichloro-2,3-dicyanopyrazine, a readily available multifunctional reagent. This reagent effectively brings both coupling partners into close proximity, facilitating dehydrative C─N coupling reactions under mild, metal-free conditions. Our approach demonstrates a broad substrate scope and enables gram-scale production. © 2025 Wiley-VCH GmbH. | |
| dc.identifier.doi | https://doi.org/10.1002/slct.202404808 | |
| dc.identifier.uri | http://172.23.0.11:4000/handle/123456789/4000 | |
| dc.relation.ispartofseries | ChemistrySelect | |
| dc.title | Transition-Metal-Free Synthesis of 7-Aminocoumarins from 7-Hydroxycoumarins Using Multifunctional Reagent |