In vitro bioactivity and physical-mechanical properties of MnO2 substituted 45S5 bioactive glasses and glass-ceramics

Abstract

MnO2 substituted 45S5 bioactive-glasses were prepared. Glass-derived Bioactive Glass-ceramics were obtained through controlled crystallization of bioactive glasses. The formed crystalline phases in bioactive glass-ceramics were identified using X-ray diffraction (XRD) analysis. In order to analyze in vitrobioactivity, bioactive glasses and glass-ceramics, before and after exposed to simulated body fluid (SBF) solution for different time periods, were investigated by fourier transform infrared (FTIR) reflectance spectrometer with measuring the pH and the concentrations of silicon, sodium, calcium, phosphorus and manganese ions in SBF solution. The density, micro hardness and flexural strength of bioactive glasses and glass-ceramics were measured. XRD results indicate the formation of crystalline phases of sodium calcium silicate in bioactive glass-ceramics. FTIR results show that in vitrobioactivity of 45S5 bioactive-glass nearly remains same by doping of 1% MnO2 by weight, but after that as well as MnO2 content increases in vitro bioactivity decreases. Crystallization of bioactive glasses decreases in vitro bioactivity. The density, micro hardness and flexural strength of bioactive glass-ceramics are higher than their respective bioactive glasses and these are also increasing with increase of MnO2 content. © 2012 American Scientific Publishers. All rights reserved.