Anti-HIV activity of some Mannich bases of Isatin derivatives

dc.contributor.author	Pandeya S.N.; Sriram D.; Clercq E.De.; Pannecouque C.; Witvrouw M.
dc.date.accessioned	2025-05-24T09:58:36Z
dc.description.abstract	A number of Mannnich bases of Isatin were synthesised and screened for anti-HIV activity. The Schiff's base derived from 5-Methylisatin and trimethoprim was converted into Mannich bases. The N-dimethyl (Pan I) and morpholino (Pan M) were the most active compounds in the series and gave maximum protection against HIV-1 (III B) strain.
dc.identifier.doi	DOI not available
dc.identifier.uri	http://172.23.0.11:4000/handle/123456789/23479
dc.relation.ispartofseries	Indian Journal of Pharmaceutical Sciences
dc.title	Anti-HIV activity of some Mannich bases of Isatin derivatives

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