Synthesis and screening for anti-HIV activity of some N-Mannich bases of isatin derivatives
| dc.contributor.author | Pandeya S.N.; Yogeeswari P.; Sriram D.; De Clercq E.; Pannecouque C.; Witvrouw M. | |
| dc.date.accessioned | 2025-05-24T09:56:46Z | |
| dc.description.abstract | The effect of about 12 new compounds of Mannich bases of isatin against HIV-1 (IIIB) and HIV-2 (ROD) strains in MT 4 cells was studied. The screening method employed was MTT. In initial studies, one compound has shown maximum protection of 16% in subtoxic concentration. | |
| dc.identifier.doi | https://doi.org/10.1159/000007182 | |
| dc.identifier.uri | http://172.23.0.11:4000/handle/123456789/21363 | |
| dc.relation.ispartofseries | Chemotherapy | |
| dc.title | Synthesis and screening for anti-HIV activity of some N-Mannich bases of isatin derivatives |