Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer’s Disease

dc.contributor.author	Venkatesh R.; Shankar G.; Narayanan A.C.; Modi G.; Sabiah S.; Kandasamy J.
dc.date.accessioned	2025-05-23T11:23:14Z
dc.description.abstract	Multicomponent synthesis of biologically relevant S-benzyl dithiocarbamates from para-quinone methides, amines, and carbon disulfide are described under catalyst and additive-free conditions. The reactions proceeded at room temperature in a short span of time with excellent yields. One of the synthesized compounds, 3e showed considerable acetylcholinesterase (AChE) inhibitory (51.70 + 5.63% at 20 μm) and antioxidant (63.52 ± 1.15 at 20 μm) activities. © 2022 American Chemical Society.
dc.identifier.doi	https://doi.org/10.1021/acs.joc.2c00423
dc.identifier.uri	http://172.23.0.11:4000/handle/123456789/8787
dc.relation.ispartofseries	Journal of Organic Chemistry
dc.title	Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer’s Disease

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