A New Avenue to the Synthesis of Symmetrically Substituted Pyridines Catalyzed by Magnetic Nano–Fe3O4: Methyl Arenes as Sustainable Surrogates of Aryl Aldehydes

Abstract

A straightforward strategy has designed for the efficient synthesis of 2,4,6–triarylpyridinesvia a three component reaction of acetophenone, methyl arenes and ammonium acetate. The total transformation is successfully achieved using a magnetic nano–Fe3O4. The method developed is sustainable, using low cost feed stocks, operationally simple, and provide good to excellent yields. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim