Antituberculous activity of norfloxacin Mannich bases with isatin derivatives

dc.contributor.author	Pandeya S.N.; Sriram D.; Yogeeswari P.; Ananthan S.
dc.date.accessioned	2025-05-24T09:58:09Z
dc.description.abstract	Mannich bases of norfloxacin were synthesized by reacting them with formaldehyde and several isatin derivatives. The compounds were evaluated in vitro against Mycobacterium tuberculosis H37Rv at 12.5 μg/ml in BACTEC 12B medium using the BACTEC radiometric system. Among the compounds tested, S-10 showed promising activity, with 100% inhibition at a concentration lower than 6.25 μg/ml. Copyright © 2001 S. Karger AG, Basel.
dc.identifier.doi	https://doi.org/10.1159/000048533
dc.identifier.uri	http://172.23.0.11:4000/handle/123456789/22945
dc.relation.ispartofseries	Chemotherapy
dc.title	Antituberculous activity of norfloxacin Mannich bases with isatin derivatives

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