The error grid analysis of invasive and indigenously developed noninvasive technique based blood glucose readings obtained from the effect of various glucose concentration sample solutions over blood glucose levels on the human subjects

Abstract

Noninvasive blood glucose monitoring technology with significant clinical accurate measurement capability should have a beneficial impact over medical care system for diabetes and its related risk managements. Moreover blood or other body fluid less technology should increase patient compliances as well as robust control over fluctuating blood glucose levels. Herein, we represent the noninvasive technology and evaluate its efficiency for detecting the respective glucose concentration induced blood glucose levels on the human subjects. The purpose of this experiment was to observe the effect of various glucose concentration sample solutions like 25gm/100ml, 50gm/100ml and 75gm/100ml over blood glucose levels on the fasting 10 human subjects during the time duration of 1hour and 2hour after respective glucose solution consumptions. Moreover, the invasive and indigenous noninvasive technology based blood glucose level readings correlations were compared and evaluated through Clarke and Parkes Error Grid analytical approaches. The experimental findings indicate that blood glucose levels increase with increase in concentration of glucose solutions in human subjects. At the same time, the blood glucose levels were regulated and controlled by the individuals' body glucose homeostasis response mechanisms. Similarly the Clarke and Parkes Error Grid analysis of the obtained invasive and noninvasive blood glucose readings showed that the measurement readings occupy the medically significant A and B zones respectively. Experimental study indicates the impact of glucose concentration over blood glucose levels and potential use of indigenously developed noninvasive technology based on amplitude modulated ultrasound with infrared technology for noninvasive blood glucose level determinations.