New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1E,6E)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione

Druzina A.A.; Zhidkova O.B.; Anufriev S.A.; Dubasova E.V.; Ananyev I.V.; Banerjee S.; Sivaev I.B.; Bregadze V.I.

doi:https://doi.org/10.3390/M1905

New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1E,6E)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione

Authors

Druzina A.A.; Zhidkova O.B.; Anufriev S.A.; Dubasova E.V.; Ananyev I.V.; Banerjee S.; Sivaev I.B.; Bregadze V.I.

Abstract

A new allyl derivative of curcumin containing three allyl groups (1E,6E)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione was synthesized by the reaction of curcumin with the excess of allyl bromide in the presence of K2CO3 in acetone under reflux. The triple-allylated curcumin was characterized by 1H and 13C-NMR spectroscopy and single-crystal X-ray diffraction analysis. © 2024 by the authors.