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Photocatalytic glucose-appended bio-compatible Ir(iii) anticancer complexes
| dc.contributor.author | Zhu Z.; Wei L.; Lai Y.; Carter O.W.L.; Banerjee S.; Sadler P.J.; Huang H. | |
| dc.date.accessioned | 2025-05-23T11:23:19Z | |
| dc.description.abstract | Rationally-designed glucose-appended Ir(iii) photo-catalysts ([Ir(N,C)2(N,N-Glc)]+, Ir1-Ir3) show visible light-induced catalytic NAD(P)H oxidation in aqueous solution. The highly in vivo biocompatible complex, Ir3, shows lysosome and mitochondria targeting necro-apoptotic photo-cytotoxicity against various cancer cell lines and multicellular spheroids, while remaining non-toxic in the dark. © 2022 The Royal Society of Chemistry. | |
| dc.identifier.doi | https://doi.org/10.1039/d2dt01134d | |
| dc.identifier.uri | http://172.23.0.11:4000/handle/123456789/8887 | |
| dc.relation.ispartofseries | Dalton Transactions | |
| dc.title | Photocatalytic glucose-appended bio-compatible Ir(iii) anticancer complexes |