Anticancer natural product from marine invertebrates

Abstract

Marine invertebrates have been used as therapeutics as well as food since a long time, because of varieties of bioactive compounds and nutrients. The invertebrate marine animals which belong to phylum Porifera, Cnidaria, Annelida, Arthropoda, Mollusca, and Echinodermata represent the animals with the richest biodiversity. These invertebrates have been identified as the main source for marine-derived drug discovery, attributing about 65% of the marine natural products reported to date. The cnidarians have described in many traditional medicine system for medicine for therapeutic use. Most of anticancer marine natural compounds have been isolated from cnidarians, especially from corals. The extensive research on marine natural compounds isolated from invertebrates has showed an opportunity for development of several potent anticancer drugs, as these molecules have been reported for their various modes of action, targeting cell receptors to genetic materials of cancer cells. The anticancer natural product isolated from marine invertebrate have described in this chapter with their mode of action and molecular targets. © 2021 Elsevier Inc. All rights reserved.