Characterisation of bioactive metabolites from endophytic bacterial isolate

Abstract

The aim of this study was to isolate and identify endophytic bacteria from stems and root of adhathoda beddomei and to evaluate their antibacterial and antifungal properties. The present investigation was carried out to analyse the morphological, physiological, biochemical and cultural characteristics diversity in the bacterial endophyte of two species of adhathoda beddomei, a total of 10 bacterial. Endophytes were isolated from tissues, stem, root. The antimicrobial and antifungal activity was tested against Escherichia coli. Pseudomonas aeroginosa, Staphylococcus aureus, Penicillium chrysogenum, Lactobacillus lactis, Bacillus subtilis and Candida albican. Minimum inhibitory concentration (MIC) of crude extract against performed microorganisms was determined. NMR, FTIR, element and mass analysis of fractionated crude extract were carried out for empirical formula and functional group. © 2017, Research Journal of BioTechnology. All rights reserved.