Electrospun Stannic Oxide Nanofiber Thin-Film Based Sensing Device for Monitoring Functional Behaviors of Adherent Mammalian Cells

Abstract

This study presents a biosensor utilizing electrospun SnO2 nanofiber films for real-time monitoring of C2C12 cells. The biosensor demonstrates sensitivity towards cellular behaviors, including adhesion, proliferation, and detachment. Alterations in semi-circle and dielectric properties are validated through Nyquist plot and an EEC model, highlighting the biosensor's potential for analyzing cellular dynamics. © 2002-2011 IEEE.