A Metal-Free System for Conversion of Alcohols to Amides Using tert-Butyl Nitrite

dc.contributor.author	Indurthi H.K.; Das S.; Saha P.; Sharma D.K.
dc.date.accessioned	2025-05-23T11:12:18Z
dc.description.abstract	A transition metal-free cascade synthesis of amides from alcohols was developed. Various alcohols reacted with N-hydroxyimides by tert-butyl nitrite to generate N-hydroxyimide esters. The resulting active esters were subsequently reacted with amines to generate amides in one pot. Further, we have illustrated the application of the developed protocol in synthesizing anti-Alzheimer compounds. A detailed mechanistic exploration was also carried out. © 2024 Wiley-VCH GmbH.
dc.identifier.doi	https://doi.org/10.1002/ajoc.202300576
dc.identifier.uri	http://172.23.0.11:4000/handle/123456789/4598
dc.relation.ispartofseries	Asian Journal of Organic Chemistry
dc.title	A Metal-Free System for Conversion of Alcohols to Amides Using tert-Butyl Nitrite

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