Bimetallic Copper/Zinc Metal Organic Framework-MoS2Nanohybrid based Electrochemical Sensor

Abstract

Acetaminophen is a globally used antipyretic analgesic drug to relieve pain. The excess usage of acetaminophen leads to various health implications including cardiovascular ailments, asthma, liver and kidney damage. Bimetallic MOFs are emerging materials in the field of electrochemical sensing domain utilizing the synergistic effect of both the metal ions present within. In this study, we report a sensing matrix comprising of an electrochemically fabricated novel bimetallic MOF (CoZn) conjugated with Mos2nanosheets to form an electroconductive nanocomposite. Layer-by-layer characterization of CoZn-MOF/MoS2modified electrode surface was done through different electrochemical analytical techniques like CV and EIS. The composite (GCE/CoZn-MOF/MoS2) can find its applications in sensing a plethora of analytes based on the catalytic potential of the metal nodes. In this work we have attempted the application of the developed nanocomposite probe in the electrochemical oxidation and thereby detection of acetaminophen. The developed nanocomposite was able to detect acetaminophen with enhancement in signal, proving the improved electroconductivity of the surface due to synergistic effect of CoZn-MOF and Mos2. © 2024 IEEE.