Chemical modification of poly (vinyl chloride) sheet with thiourea for cell study

Abstract

Plasticized poly (vinyl chloride) has been used as biomaterial to make medical equipment. An appropriate reaction situation by temperature at 60-85°C for the surface modification of PVC sheet with sodium thiourea has been investigated. Although, the use of a phase-transfer catalyst (Tetra butyl ammonium hydrogen sulphate-TBHAS) makes it feasible for the nucleophilic substitution reaction to take place, the morphology of the film is changed by the reaction, leading to a loss in both surface smoothness and transparency of the film. According to this study, the reaction with sodium thiourea occurs consistently through the sheets, and modified surface have antibacterial capacity. © 2013 AIP Publishing LLC.