Redox electrochemistry of electrodes tuned with dimethyl ferrocene based on Co–NC–Pd nanogeometry: an impedimetric sensor for NADH sensing

Abstract

Cobalt N-doped carbon (Co–NC) and palladium (Pd) nanoparticles were used to modify the CPE, which served as a platform for sensing the NADH. The use of this sensor offered the advantages of improved electrochemical stability, simple fabrication, and low cost. Here, we present a straightforward, accurate, and sensitive approach for measuring NADH in neutral PBS utilizing an electrochemically altered carbon paste electrode. The synthesized materials have been characterized using HR-SEM, TEM, and XPS. Electroanalytical approaches like Cyclic voltammetry, Amperometry titration, and EIS have been carried out to check out the activity of the modified electrode. The modified electrode becomes more electroactive towards NADH oxidation due to the interaction of Co–NC/Pd with dimethyl ferrocene, with a notable reduction in the peak potential difference occurring despite electrode fouling. The sensor has a high electrocatalytic response and a detection limit of 2 µM throughout a broad linear range up to 5 to 1250 µM with a correlation coefficient of 0.989. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.