A concise report on pharmacological and bioanalytical aspect of sinigrin

Abstract

Sinigrin (Allylglucosinolate) is precursors of the anticancer compounds allyl isothiocyanate which is found in Brassica juncea, Phyllanthus emblica, Armoracia lapthifolia, Wasabia japonica and some other plants. Except its uses as a medicinal compound it aslo have nutraceutical value. It protects plant from fungi, nematodes, plant pathogens and herbivores. Allyl isothiocyanate is produced from sinigrin through plant myrosinase or microbial myrosinase in gut microflora. Sinigrin have various type of pharmacological activity such as anticancer, antimicrobial and it suppresses NO production in the macrophages. This review will provide a brief idea about isolation techniques, analytical aspect and pharmacological activity of sinigrin. The data were collected from the available literature source in regards with sinigrin and it can be helpful to the researchers to get some idea about this unique phytoconstituents. © 2012 Asian Pacific Tropical Biomedical Magazine.