N-nitrosamine directed stereoselective O-glycosylation reactions of 2-amino thioglycosides with NIS-TfOH

dc.contributor.author	Kanaujiya V.K.; Lai C.-H.; Kandasamay J.
dc.date.accessioned	2025-05-23T10:56:35Z
dc.description.abstract	We described here the stereoselective synthesis of O-glycosides from 2-amino thioglycosides using N-nitrosamine as the directing group. The reaction was activated by using the NIS/TfOH system in dichloromethane at −10 °C. Various sugar and non-sugar acceptors were successfully glycosylated with 2-amino 1-thioglucoside and 2-amino 1-thiogalactoside under mild reaction conditions. These reactions provided β-glycosides in good to excellent yields. © 2025 Elsevier Ltd
dc.identifier.doi	https://doi.org/10.1016/j.carres.2025.109435
dc.identifier.uri	http://172.23.0.11:4000/handle/123456789/4051
dc.relation.ispartofseries	Carbohydrate Research
dc.title	N-nitrosamine directed stereoselective O-glycosylation reactions of 2-amino thioglycosides with NIS-TfOH

Collections