Synthesis of N-Phenylazo (Triazine) Derivatives of 6-Aminouracil Using Diazonium Salt Under Catalyst-Free Condition

Abstract

In the current study, for the first time, N-phenylazo (triazine) derivatives of 6-aminouracil compounds were produced at room temperature under catalyst-free conditions in pyridine using an easy, efficient, and green process. The main advantages of this approach are that it doesn't require a catalyst, is inexpensive, eco-friendly, non-toxic, and simple to handle. This technique shows a broad range of substrate compatibility for uracil compounds and diazonium salts. © 2024 Wiley-VCH GmbH.