Isolation of a new cytotoxic colchinoid from Gloriosa superba roots

dc.contributor.author	Goel, Bharat
dc.contributor.author	Reddy, Harichander
dc.contributor.author	Cholkar, Anjali
dc.contributor.author	Kumar, Sanjeev
dc.contributor.author	Guru, Santosh Kumar
dc.contributor.author	Jain, Shreyans K.
dc.date.accessioned	2023-04-25T09:06:49Z
dc.date.available	2023-04-25T09:06:49Z
dc.date.issued	2022
dc.description	This paper is submitted by the author of IIT (BHU), Varanasi	en_US
dc.description.abstract	A new colchinoid compound, identified as N-deacetyl-N-formylcornigerine (1), named glorigerine was isolated from the roots of Gloriosa superba, along with two known compounds. The structures of isolated compounds were elucidated by 1 D and 2 D NMR and HRMS experiments. Glorigerine (1) differed from cornigerine (6) by the presence of an N-formyl group instead of the N-acetyl group. Glorigerine (1) was found to have moderate cytotoxicity when tested against four human cancer cell lines.	en_US
dc.identifier.issn	14786419
dc.identifier.uri	https://idr-sdlib.iitbhu.ac.in/handle/123456789/2247
dc.language.iso	en	en_US
dc.publisher	Taylor and Francis Ltd.	en_US
dc.relation.ispartofseries	Natural Product Research;
dc.subject	colchinoid	en_US
dc.subject	cytotoxicity	en_US
dc.subject	glorigerine	en_US
dc.subject	Gloriosa superba	en_US
dc.subject	natural product	en_US
dc.title	Isolation of a new cytotoxic colchinoid from Gloriosa superba roots	en_US
dc.type	Article	en_US

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