Determination of glucose concentration in various optical phantoms by indigenously developed ultrasound collaborated infrared technology

Abstract

The advent of a successful noninvasive blood glucose determining technology would revolutionize the diabetes management protocols. Here indigenously developed techniques based on amplitude modulated ultrasound with infrared technique have been utilized to detect particular glucose concentrations in various phantoms. This research paper explains the impact of the glucose concentration determinations in different types of optical tissue property resembling phantoms. Various samples utilized here were distilled water, commercializedized milk, chicken breast tissue and human whole blood. Concentrations of the glucose molecules were varied in phantom samples and its effects were observed through indigenously developed modulated ultrasound and infrared technique based unit. Actually, in the indigenously developed unit, the ultrasound in modulating wave characteristics generates molecular vibrations throughout the phantom sample. The infrared light captures the glucose based vibrational patterns in solitary mode to yield the amount of glucose concentration present in various phantom samples. The result signifies the good functioning effectiveness of our indigenously developed MUS-IR (Modulated Ultrasound-Infrared) unit for measuring Dextrose (glucose) concentrations in particular optical phantoms. In near future, this new hybridized technology of ultrasound and infrared units could be helpful for designing and developing noninvasive blood glucose monitoring devices.