An easy and efficient protocol for the condensation reaction of isatin and N-substituted isatins with 1,2-diaminobenzene using low cost reusable clay catalyst

Abstract

A green procedure was developed for the condensation of isatin and N-substituted isatins with 1,2-diaminobenzene by using reusable bentonite clay in EtOH/H2O solvent system, under microwave irradiation. This eco-friendly synthesis is characterized by high yields and short reaction times. The catalyst is easily recycled. © 2014 by Walter de Gruyter Berlin Boston.